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This booklet constitutes the second part of the World Drug Report 2018. It provides a global overview of the latest estimates of and trends in drug use and drug supply, as well as of several cross-cutting issues related to the world drug problem. Such issues comprise the health impact of drug use, including trends in drug use disorders, problem drug use as reflected in treatment demand and estimates of the number of people who inject drugs (PWID) and of those living with HIV and hepatitis. The present booklet also examines the global extent of deaths attributable to drug use, with recent trends in overdose deaths in some countries being presented as illustrative. Information on witnessing an overdose or personally experiencing a non-fatal overdose is also presented. A review of the availability and levels of coverage of core interventions (particularly needle and syringe programmes and opioid substitution therapy) to help prevent the spread of HIV and HCV among PWID is also included. Finally, the booklet contains a global overview of the latest estimates of and trends in cultivation, production and trafficking of illicit drugs, including on the Internet, using the darknet.
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