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December 2020 – WHO: World Health Organization recommends 8 NPS for scheduling

GENEVA, Switzerland – December 2020: Since its start in 2013, the UNODC Early Warning Advisory on NPS regularly provides scientific information to Member States and the World Health Organization (WHO) for the identification of the most harmful, prevalent and persistent NPS in support of review processes for national and international control. The WHO has announced the scheduling recommendations on psychoactive substances reviewed at the 43rd Meeting of the WHO Expert Committee on Drug Dependence (ECDD) held in a virtual format in Geneva from 12 to 16 October 2020. In total, eleven substances were critically reviewed by the ECDD and eight substances were recommended for scheduling:

Single Convention on Narcotic Drugs of 1961, as amended by the 1972 Protocol:
Isotonitazene - (Schedule I)

Convention on Psychotropic Substances of 1971:
CUMYL-PeGACLONE - (Schedule II)
MDMB-4en-PINACA - (Schedule II)
3-Methoxyphencyclidine (3-Meo-PCP) - (Schedule II)
Diphenidine - (Schedule IV)
Clonazolam - (Schedule IV)
Diclazepam - (Schedule IV)
Flubromazolam - (Schedule IV)

The WHO recommended that 2-MeO-diphenidine, 5-Methoxy-N,N-diallyltryptamine (5-MeO-DALT) and 3F-Phenmetrazine (3-Fluorophenmetrazine, 3-FPM) should be kept under surveillance.



For more information, please see:

Recommendations of the 43rd Expert Committee on Drug Dependence

Annex 1: Summary assessment and recommendations of the 43rd Expert Committee on Drug Dependence


UNODC Current NPS Threats Volume III

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